Jarrad T. Hampton-Marcell

Humans harbor as many microbial cells as their own, and the microorganism residing in the gastrointestinal tract - commonly referred as the Gut microbiome - harbor a functional 150 times the capacity of the human genome. The associations between the gut microbiome composition and disease status are well-reported demonstrating influence on remote organs, mucosal, and immune function. This has led to the development of studying host-microbe interactions in the context of health outcomes.

I am interested in leveraging gut microbial ecosystems to to restore health and prevent disease at both macro and micro scales. With a specific interest in environment, exercise, and nutrition, we elicit microbial mechanisms that govern the gut-muscle and gut-brain axes. We utilize in vivo (human and murine models), in vitro (anaerobic bioreactors), and bioinformatic approaches (machine learning) to uncover the translational potential of the gut microbiome on human health with an emphasis on microbial-derived short chain fatty acid and branched chain amino acid producers.